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Dabrafenib treatment significantly upregulated the expression of Axl receptor tyrosine kinase (Axl) in the spinal cord tissues of EAE mice, increased the expression of System Xc , GPX4, and Ferritin, and decreased the expression of CD71, ACSL4, and POR

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Statistical analysis The pooled trial participants were stratified according to baseline FI into 3 categories: nonfrail (FI 0.210), more frail (FI: 0.211-0.310), and most frail (FI 0.311)

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