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doi:10.1177/03000605231177191 20

That said, this comparison is not as simple as tirzepatide wins, use tirzepatide. The full picture is more nuanced, and I want to give you an honest account of both what the data shows and what I actually see in our clinics

When muscle is lost during weight management, it can result in: Decreased metabolic rate Reduced physical strength and endurance Difficulty maintaining weight loss long-term Diminished quality of life and functional capacity For those using medical weight management approaches, these concerns become even more pressing, as the accelerated weight loss can sometimes lead to greater muscle breakdown without proper nutritional support

In adults, it lowered total daily insulin needs by 0.44 units per kg

Wegovy has a shorter room temperature window of 28 days at the same temperature ceiling