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Dyspepsia, characterized by upper abdominal discomfort, early satiety, or postprandial fullness, may affect a similar proportion of patients and can contribute to reduced caloric intake and weight loss, though it may also impact quality of life if severe or persistent

Therefore, it is necessary to understand how a variety of intrinsic and extrinsic factors are integrated to create the metabolic flexibility and to reduce the metabolic dependencies dictated by oncogenic signaling

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406,407,408 Microbial metabolites, such as short-chain fatty acids (SCFAs), play a significant role in neuroinflammation and nerve regeneration

For prescribers, the clinical demand is clear