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Quick Answer: Unopened semaglutide remains stable until the printed expiration date when refrigerated, while opened Ozempic pens are effective for 56 days after first use

Take the tablet with a small amount of water (no more than 4 ounces, or 120ml)

Depending on the molecular properties (33), these agonists exert their effects by activating GLP-1R + glutamatergic neuronal populations (70, 71), but not GABAergic neurons (72)

There are also some older GLP-1 medications, but they are less effective than the newer options