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Cardiovascular and neurovascular injury: Protection in heart ischemia models, eye injuries, and various CNS insults through combined vascular, antiinflammatory, and antioxidative mechanisms
This extends the photoprotective role of sunscreens to the visible & IR spectrum as traditional ingredient only protect against UVB & UVA
Hydration is critical
Mechanistically, this redoxin directly reduces lipid hydroperoxides [180,181] , alleviates ferroptosis-induced mitophagy [182] , remodels membrane phospholipid composition [183] , or diminishes inflammatory pathways [173,176]
however, evidence is emerging that increased cellular GSSG accumulation may be of equal, if not greater, importance in regulating oxidative stress-triggered detrimental effects
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