Ipamorelin produces a rapid, selective GH pulse in with a short terminal half-life (~2 hours) and minimal off-target pituitary effects, supporting tightly timed pulse experiments
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The vagal parasympathetic stimulation by SMT, could then release neurotrophins ( brain-derived neurotrophic factor , BNDF and nerve growth factor , NGF) to help resolve depression and related neuro-cognitive impairments 779