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Safety data that was downplayed in FDA submissions
Additional considerations include diabetic retinopathy status (semaglutide may worsen retinopathy in some patients with pre-existing disease, particularly with rapid A1c improvement), history of pancreatitis (use GLP-1 agents with caution), and upcoming surgical procedures (discuss with your surgical/anesthesia team due to effects on gastric emptying)
A Harvard Health blog and a Mayo Clinic commentary recommend focusing on proper nutrition, regular exercise, and sleep rather than seeking an instant glow from an IV drip
This underscores the urgent need for safe, effective, and sustainable pharmacological interventions
Chen C, Yang K, He D, Yang B, Tao L, Chen J, et al
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