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see MIC Injections for typical timelines and schedules

Speak with an endocrinologist or diabetologist to determine which option is right for your condition.

[END CALLOUT BOX] GLP2 Pharmacokinetics & Metabolism Absorption & Distribution Following subcutaneous administration, GLP2 exhibits favorable pharmacokinetic properties enabling once-weekly dosing: Mean absolute bioavailability of approximately 80% after subcutaneous injection Time to maximum plasma concentration (Tmax) ranges from 8 to 72 hours Steady-state plasma concentrations achieved after 4 weeks of once-weekly dosing Mean steady-state volume of distribution approximately 10.3 L, indicating limited tissue distribution The high plasma protein binding to albumin (99%) results from the C20 fatty diacid modification, which provides prolonged systemic exposure and enables sustained therapeutic effects between weekly doses

1 September 2005

People with a history of certain thyroid cancers or pancreatitis, for example, may not be eligible for this treatment