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The dose itself might not change dramatically from the systemic protocol (e.g., 250-350mcg total per day), but the location of the administration is the key variable
A lyophilized product will have a different weight compared to its original state, meaning that care must be taken when measuring out the right amount of bacteriostatic water for reconstitution
Typically, the dose is increased every month until a long-term maintenance dose is reached, but the timeframe can be customized to your needs
PMCID: PMC4772032
Scand J Gastroenterol 31: 665-670, 1996
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