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The side effects may be reduced when patients begin therapy at low doses and increase to higher doses slowly over time. Patients should also be evaluated for misuse risks, adds Devnani, as some patients may become addicted to the drugs

Low levels of FLNA, causing loss of coupling of SSTR2 with downstream signal transduction molecules, might explain the resistance to SS analogs in GH-secreting pituitary tumors even if in the presence of SSTR2

Off-label weight-loss use is not a covered indication under any HCSC-operated plan

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That's $15,600 annually for medication that requires continuous use to maintain results