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The study reported a significant reduction in the frequency and severity of muscle cramps in the participants who received L-Carnitine
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In addition to BRCA genes, mutations in other high-penetrance genes such as TP53 (associated with Li-Fraumeni syndrome) and PTEN (linked to Cowden syndrome) have been found to be associated with familial breast cancer, as these genes are heritable, keeping women at potential risk to develop cancer during their lifetime ( PALB2, ATM , and CHEK2 (63)
Weight loss at 24 weeks (primary endpoint): Weight loss at 48 weeks (secondary endpoint): The weight loss curves had not plateaued at 48 weeks
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