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Comparison of pooled cohort equation and PREVENT risk calculator for statin treatment allocation
(2) ROS activates NF-B and MAPK signaling pathways, upregulating the expression of MMPs (MMP-13, MMP-3) and inflammatory factors (IL-1, TNF- ), thereby accelerating the degradation of type II collagen (Col-II) and proteoglycans
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This random assignment ensured that half of the participants started the study with morning injections and the other half with evening injections.The schedules were standardized to 08:0009:00 and 20:0021:00, respectively, according to the patient's age
By reducing melanin production, glutathione helps gradually lighten the skin
