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Acting on hypothalamic and reward pathways, GLP-1RAs promote satiety and reduce anticipatory food rewards [19, 23]

[2] [28] Conversely, an acidic pH means the drug is predominantly in a water-soluble cationic (salt) form, and less is absorbed

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Future studies should prospectively assess emotional eating, binge-eating symptoms, psychiatric comorbidity, reward sensitivity, learned dietary patterns, and baseline food preferences alongside taste perception, satiety, nausea, liking, wanting, and weight outcomes