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The mechanism involves both weight loss and direct effects on inflammation, endothelial function, and atherosclerotic plaque stabilization

However, other factors like immobility, genetic predisposition, and hormonal influences also affect clot risk independently of hydration status

Clinical Highlights Phase 2 data showed that individuals receiving the 4.8 mg dose weekly for 46 weeks achieved nearly 19 % average weight loss vs placebo

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Demonstrate pen use and have patients perform return demonstration