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For women navigating weight management alongside hormonal changes, the intersection of metabolic peptides and hormonal health adds another layer of complexity
Research showed that weight regain is common after discontinuing semaglutide (a common GLP-1 medication), with people regaining two-thirds of the weight they lost, and improvements in risk factors like blood pressure and HbA1c also reversed
Tirzepatide often delivers greater weight loss and glucose control, while semaglutide has proven cardiovascular benefits for certain high-risk patients
Restarting or switching therapies common after GLP-1 discontinuation Among patients who discontinued tirzepatide or semaglutide within the first year of treatment, many restarted the original medication or switched to another treatment
Topical patches have different risk considerations than oral or injected medications
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