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Lugano R, Ramachandran M, Dimberg A
podra surgir tolerancia (aunque algunos sugieren que no provoca tolerancia fcilmente, esto no es consenso)
Phase 3 REDEFINE trials enrolled over 3,400 participants with 68-week follow-up
Statements Data availability statement The original contributions presented in the study are included in the article/ Supplementary Material
Melatonin exerts its analgesic actions not by binding to opioid receptor subtypes but by increasing the release of beta-endorphin an endogenous opioid
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