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Preventing constipation involves three main pillars: staying highly hydrated, maintaining a consistent (but not excessive) intake of soluble fiber, and engaging in regular physical activity
Furthermore, the study also reported that antidepressants may diminish the weight-loss effects of GLP-1 receptor agonists, potentially leading to a discrepancy between users expectations of treatment efficacy and their actual experience
The new drugs, which were originally developed to treat diabetes, are targeting the biology that makes weight so hard to lose and keep off: They dial down hunger in the brain, slow gastric emptying, and improve post-meal insulin signaling
Mild nausea, stomach upset, constipation, or fatigue can occur, especially early on