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The extra fluid volume can stress an already compromised cardiovascular system

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Rapid weight loss produces facial volume changes (Ozempic face) and muscle loss, both partially preventable with slower titration and resistance training

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Activation of NTSVTA projections attenuates cocaine seeking via a GLP-1-dependent mechanism of action in the VTA Our next goal was to determine if the suppressive effects of activating NTSVTA projections on cocaine seeking were due to increased GLP-1 signaling in the VTA

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