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Anti-inflammatory effects of GLP-1 medicines independent of weight loss Several GLP-1 medicines, including semaglutide, liraglutide, and exenatide, reduce plasma levels of C-reactive protein (CRP), a surrogate of systemic inflammation, in people with obesity or T2D
The renal fibrosis genes Fn1, Serpine1, Tgfb1, and Col1a1 were downregulated, and the degree of fibrosis was milder
Antiplatelet agents and statins were more often administered in SGLT2i group
It also helps to regulate cholesterol and triglyceride levels and helps support heart muscles
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