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Despite its widespread use in cell culture studies, SLC7A11 inhibitor Erastin cannot be used for animal studies due to its poor metabolic stability and low solubility in vivo [13]
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Pyridoxine is a water-soluble vitamin and is one of the three naturally occurring forms of vitamin B6 (pyridoxine, pyridoxal, and pyridoxamine)
A two-year clinical trial designed to assess the effect of lipoic acid (1,200 mg/day) on loss of mobility and changes in brain volume in patients with progressive multiple sclerosis is ongoing (85)
Baggio LL, Drucker DJ (2021) Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease
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