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Cys151 residue is required to inhibit Keap1-mediated Nrf2 degradation, thus itaconate upregulates Nrf2 levels via Keap1 alkylation ( Figure 3 )

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Protection contre l'inflammation Le stress oxydatif est souvent l'origine d'une inflammation chronique, qui peut se manifester par une fatigue accrue, des douleurs corporelles et une rcupration plus lente

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