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The most common type of TEAE in the semaglutide group, and thus the primary reason for the difference in incidence of TEAEs between the treatment groups, was gastrointestinal, reported in 19 (51.4%) participants in the semaglutide group and six (15.8%) participants in the placebo group
Importantly, the largest reductions in BMI were observed in the southern United States, which also reported the highest rates of GLP-1 RA dispensing claims (Rader et al., 2024), a geographic concordance that is consistent with a causal contribution of these pharmacotherapies to the observed population-level BMI decline
Consumption of the non-nutritive sweetener stevia for 12 weeks does not alter the composition of the human gut microbiota
Its an intriguing idea, but much of this messaging oversimplifies how GLP-1 actually works in the body
If you experience persistent blood glucose readings above 15 mmol/L with symptoms or ketones present, seek same-day clinical advice from your GP, urgent care centre, or NHS 111
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