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Most B12 in the UK is injected into muscle, but the fatty subcutaneous route is a recognised alternative

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The increasing scale of this phenomenon, dynamic changes in the market for falsified and illegally traded products, and threats to the health and life of people receiving such products imply the urgency of systematic monitoring of both legal and illegal chains of medicinal products

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Special population studies, including evaluation in elderly patients, patients with significant comorbidities, and patients with organ dysfunction, would help establish safety profiles for diverse clinical populations