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Balanced blood glucose levels

Adult Bbs5 -null mice are morbidly obese, hyperphagic, glucose intolerant, and have behavioral and learning impairments

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Furthermore, both SM and exenatide selectively activated p38 MAPK phosphorylation in the spinal cord, providing additional evidence that SM exerts its anti-allodynic effects by targeting spinal GLP-1R and promoting microglial -endorphin synthesis via the p38 MAPK signaling cascade [72]

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