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Accessed on May 14, 2025 at Trulicity [package insert]

Positioning, supportive pillows, ice or heat before bed reducing nighttime discomfort

Skin irritation and rashes Following skin-whitening injections, some patients may develop skin rashes, redness, or irritation

Insurance coverage remains uncertain until FDA approval

inferred from weight-loss magnitude and class data Testosterone effect in men / weight loss of 10%+ raises free testosterone by roughly 2 to 3 nmol/L in prior obesity trials SHBG change / adiposity reduction consistently raises SHBG, increasing bioavailable androgens Women / fat-mass loss of this magnitude can restore LH pulsatility and ovulatory cycles in hypothalamic amenorrhea PCOS relevance / GLP-1-class agents reduce androgen excess and improve menstrual regularity Cardiovascular link / erectile dysfunction shares endothelial risk factors