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126 Co-administration of warfarin (a substrate of CYP1A2, CYP2C9, and CYP3A4) and octreotide led to high INR levels in humans, which may be attributed to the increased warfarin exposure caused by octreotides inhibitory effect on CYP3A4
Its also considered relatively safe under medical supervision during pregnancy
Approximately 40% of individuals with FHI do not have an identifiable mutation in any of the genes known to be associated with FHI
They feed into one another, amplifying emotional reactivity, sensory overload, and developmental strain
This altered alcohol tolerance may be due to weight loss, reduced food intake, and slowed stomach emptying caused by the medication
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