Water, Glycerin, Butylene Glycol, Methylpropanediol, Niacinamide, 1,2-Hexanediol, Chondrus Crispus, Chondrus Crispus Extract, Hydroxyacetophenone, Ceratonia Siliqua (Carob) Gum, Xanthan Gum, Glucomannan, Allantoin, Sodium Citrate, Potassium Chloride, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, Ethylhexylglycerin, Adenosine, Sodium Phytate, Glutathione, Hydrolyzed Collagen, Maltodextrin, Citric Acid, Collagen, Sodium Ascorbyl Phosphate, Ascorbyl Glucoside, Hydrogenated Lecithin, Magnesium Ascorbyl Phosphate, Disodium EDTA, Ceramide NP, Ascorbic Acid, Biotin, Cyanocobalamin, Folic Acid, Pyridoxine, Riboflavin, Thiamine HCl Ingredient lists may be updated or changed at the manufacturers discretion
Before imaging, the cells were incubated with 100 nM TRaQ-G or TRaQ-G-ctrl ligand for 1 h in culture medium still containing thymidine
Common Side Effects Reference When to Adjust Protocol The vast majority of GHK-CU users experience no significant side effects
3 Results In this study, we aimed to determine if three drugs from the SSRI family (sertraline, fluoxetine, and citalopram), commonly used as antidepressants (Figure 1, right panel), can be repurposed as inhibitors of MRP1 and MRP7 transporters (Figure 1, left panel) to overcome MDR in cancer cells
While the cancer cells provide their microenvironment with secreted metabolites, sertraline treatment could target the galectin-1 mediated immunosuppressive marks of ser/gly metabolically dependent lung cancer [35, 67]
