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[5] That finding should not be expanded into a universal claim that AOD9604 directly activates CPT1, increases mitochondrial number, induces oxidative gene expression, or increases fatty-acid oxidation in every tissue or model
Briefly, the mean (standard deviation [SD]) age was similar between the two cohorts at 47.8 (10.3) years of age in the semaglutide 2.4 mg cohort and 49.5 (10.9) years of age in the tirzepatide cohort
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Treated mice show a 15%20% increase in basal metabolic rate and elevated energy expenditure, with effects positively correlated with NNMT inhibition
