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FOXO4-DRI is a roughly 5.4 kDa, strongly cationic TAT-fusion peptide, and cationic peptides tend to bind extracellular matrix at the injection site, so subQ delivery could plausibly be substantially lower than IV
10.1042/bj0291602 Biochem J
Also, the dose for humans could lead to an overdose in dogs.
Your administration method dictates your protocol
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