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Bioinformatics analysis (UbiBrowser) and literature mining were used to predict potential FBXO22-regulated targets, including KDM4A, p53, CD147, PTEN, BAG3, LKB1, KLF4, BACH1, Snail, and HDM2
The most extensively documented involves upregulation of vascular endothelial growth factor (VEGF) and its receptor VEGFR2, promoting angiogenesis, the formation of new blood vessels, in injured tissue
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Skin Firmness and Texture: It improves elasticity, thickness, and hydration, countering sagging and roughness
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