Of the tirzepatide-treated groups, 71.7%,78.3%, and 76.6% in the 5-mg, 10-mg, and 15-mg groups, respectively, met this endpoint compared with 36.7% in placebo
Its prescribed under the brand name Wegovy for weight loss and Ozempic and Rybelsus for treatment of type 2 diabetes (Rybelsus is an oral version as opposed to an injectable)
Managing side effects : Common adverse effects of Wegovy include: Nausea, vomiting, and diarrhoea (usually transient and improving over time) Constipation Abdominal discomfort Fatigue Some of these symptoms overlap with hypothyroidism symptoms, which can make it challenging to distinguish between inadequate thyroid replacement and medication side effects
These results indicate that GLP1RAs have therapeutic effects against EndMT, an important process in atherosclerosis and fibrotic diseases
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