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[2] AOD9401 was investigated separately in Zucker fatty rats and isolated adipose tissue
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Originally developed as an anti-obesity drug, AOD-9604 is a synthetic fragment derived from human growth hormone (hGH), specifically the 177-191 amino acid sequence
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Although fundamental 5A-1MQ and LD-mediated changes to the microbiome were identified, this work is similar to many current studies where further investigations will clarify if changes in the microbiome are causative or associative 100
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