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A geometrical constraint (along dihedral angles and ) was applied to facilitate the conformational change along a pre-defined pathway from the starting conformer (T or R) to the known target conformer (R or T)
Giblin JT, et al
This stable gastric penta-decapeptide was used also to provide new insights in treatment of colitis and ischemia and reperfusion in rats, where it was able to quickly restore blood supply to the ischemically injured areas and rapidly activated the growth rate of collateral blood vessels involved the NO system
In simple terms, peptides are chains of amino acids, smaller than proteins, that play a vital role in various bodily functions
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