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Renal Transporters and Disease Renal Tubular Acidosis, RTA Metabolic acidosis can result from the accumulation of acids, predominantly H + , or from the excess loss of bicarbonate (HCO 3 )
This age-related decline correlates temporally with diminished tissue repair capacity, though causation remains debated in gerontology literature
Free radicals are widely thought of as the force working against healthy aging and antioxidants as the supporting force
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