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High dose oral cobalamin would be a reasonable alternative as maintenance in patients unable to tolerate intramuscular injections provided there is good compliance with treatment
When selenium is reduced, some selenoproteins in the body quickly disappear (low grades), while others can continue to be synthesized even when selenium levels are reduced (high grades) ( GPX2 was the first selenoprotein identified as a target of the Wnt pathway, and its promoter contains five -catenin/TCF binding sites (TBE) (Prez et al., 2017)
Carnitine transports fatty acids to the mitochondria where they undergo beta-oxidation for energy
Baltimore et al., 1987
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