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ALLO impairs memory acquisition/encoding in rodent models when it is injected into the nucleus basalis magnocellularis before an acquisition trial, implicating inhibition of cholinergic neurotransmission in the effects of ALLO on memory acquisition (181)

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This metabolic safety profile makes AOD-9604 potentially suitable for individuals with metabolic syndrome or diabetes risk factors who might not tolerate traditional growth hormone therapy, though medical supervision remains appropriate

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