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Phase 3: therapeutic escalation (weeks 9 through 16) Daily dose: 5 to 8 mg sublingual This phase is where results accelerate

Current prescribing restrictions, which are largely based on BMI thresholds or weight-loss targets, may not be appropriate, as patients with established cardiovascular disease might benefit regardless of their weight-loss response

However, challenges such as gastrointestinal side effects and high medication costs are limiting broader accessibility

Doctors may notice better metabolism markers like A1C and cholesterol levels

While the initial results of clinical trials are promising, the long-term efficacy and sustainability of GLP-1 analogue treatments depend on the adoption of healthy lifestyle changes