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Animals developed persistent esophagitis with hemorrhagic lesions, thinned epithelium, and chronically reduced sphincter pressures lasting up to 20 months

doi: 10.1016/j.omtn.2019.11.015 262 YanSWangPWangJYangJLuHJinCet al

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a novel small molecule peptide classified as an NNMT inhibitor meaning it blocks the activity of the enzyme nicotinamide N-methyltransferase (NNMT), which plays a key role in cellular energy metabolism , fat storage , and aging

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