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(1997, Journal of Endocrinology) reported that IGF-1 LR3 supported protein turnover in tumor-bearing catabolic rats but also increased tumor growth in that model

10.1038/srep28675 Marconi B, Bobyr I, Campanati A, et al.: Pseudoxanthoma elasticum and skin: Clinical manifestations, histopathology, pathomechanism, perspectives of treatment

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