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A 2012 meta-analysis published in the Journal of Ethnopharmacology reviewed 14 randomized trials involving berberine supplementation
I generally recommend starting at 0.25 mg for the first week regardless of injury severity
That will depend on what your insurance covers, and which medication you choose
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Just like we have learnt to advise hypertensive or hyperlipidemic patients on a healthy lifestyle but start therapy immediately, we need to recognize that many obese patients have wrestled with this for a lifetime, have tried multiple lifestyle interventions already
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