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TABLE 3 Factors associated with anxiety incidence in diabetes patients with/without GLP1-RA: subgroup analysis
Consistent with known functions of the GSTs, several differentially regulated pathways and processes were associated with lipid metabolism and with the oxidative stress response, while additional interesting associations suggested altered cell cycle regulation and differences in apoptosis, cell invasion and migration
Amyotrophic lateral sclerosis and oxidative stress: a double-blind therapeutic trial after curcumin supplementation
Available information indicates comparable safety
Proinflammatory cytokines TNF- and IL1- activate the canonical NF-B pathway that induce the gene expression of cyclooxigenase-2, inducible nitric oxide synthase-3, inflammatory cytokines, and matrix metalloproteinases [75] These changes lead to the damage of TJs, decreased endothelial integrity and increased permeability at the BBB [73, 76], and to neuroinflammation and the development of chronic neurodegenerative diseases such as AD [10, 77]
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