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Notably, at physiological concentrations, TMAO can enhance the integrity of the bloodbrain barrier through the tight junction regulator annexin A1, limit the reactivity of astrocytes and microglia, and protect the cognitive function of mice from inflammatory challenges
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In a 10-week trial, participants taking the extract showed the following results: over 10 weeks measured at 10 weeks average across participants supports appetite regulation *Results based on a 10-week clinical study of African Mango extract
Safety analysis Amongst the 16 safety domains (Supplementary Material 7), most of the side-effects were related to the gastrointestinal system
