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Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]

(2025) 48:S86s127

Peak plasma salicylate concentrations from aspirin overdose may not be reached for 4-35 h after ingestion

A peptide cannot replace a correct diagnosis

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