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The general characteristics are summarized in Table 1

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LncRNAs, typically exceeding 200 nucleotides, not only regulate gene activity near their synthesis site or at distant locations but also act as sponges to bind miRNAs, thereby inhibiting their ability to regulate other target mRNAs

To optimize absorption and minimize local irritation, it is recommended to rotate injection sites, such as the upper arms, thighs, and areas around the navel

The clinical evidence base for topical use is stronger than for injection