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Human eNOS+ enteric neurons in the submucosa also express the GLP-2R, supporting a direct role for GLP-2-mediated increase in eNOS protein and NOS release through cAMP-dependent protein kinase A (Guan et al., 2006) (Table 3)

This is the alternative pathway

Activation of GLP-1 Receptor Promotes Bone Marrow Stromal Cell Osteogenic Differentiation through -Catenin

Dehydration GLP-1 medications can cause dehydration through reduced fluid intake (you are simply drinking less) and increased fluid loss (particularly if GI side effects are present)

Liraglutide Efficacy Profile: A Network Meta-Analysis