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G., and Paz-Ares, L
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Alteration in insulin signaling may accelerate the onset of Alzheimers disease, by changing the intracellular concentration of neurotransmitters involved in memory formation and functioning, and influencing on amyloid--related processes and amyloid clearance (Craft, 2007
Finally, in terms of inhibition induced by inflammatory cytokines, chronic exposure to proinflammatory cytokines such as TNF-, could suppress pituitary ACTH secretion and thus, cause relative hypocortisolism during chronic infections (36, 4346)
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