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Published January 18, 2024

Semaglutide GLP-1 works by mimicking a naturally occurring hormone in the body called GLP-1 (glucagon-like peptide-1)

In human studies lasting 812 weeks, daily doses of 412mg have been associated with small improvements in elasticity, hydration, and wrinkle depth, as well as reduced skin dryness following UV exposure.1 25 Researchers attribute these changes to reduced collagen breakdown and improved moisture retention in the skin barrier

Developed by Eli Lilly and currently in Phase 3 clinical trials, it functions as a triple agonist, simultaneously activating three distinct receptor types that regulate appetite, metabolism, and energy expenditure

This endogenous nature distinguishes GHK-Cu from many synthetic peptides and is one reason for the broad research interest