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In this study, we analyzed the methylation level of 76 CpG sites (6 CpG islands) within the promoters I, II, IV, and VI and the exonic regions following leptin treatment

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[23] AP1 via Ref1 Trx1 indirectly increases the DNA-binding activity of activator protein 1 (AP1) by reducing the DNA repair enzyme redox factor 1 (Ref-1), which in turn reduces AP1 in an example of a redox regulation cascade

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