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And perhaps most important, was the test done at a time where the gastrointestinal tract still suffered from lack of B12, and because of that had a temporary decreased capacity for uptake of B12
Confirmatory diagnostic studies should be performed prior to initiating therapy, if possible, and the patient should be followed with appropriate studies to demonstrate hematologic improvement (Hgb, hematocrit, RBC, reticulocyte count)
It is relevant because NNMT is overactive in fat tissue during obesity
Early Phase (Weeks 1 to 3) The first few weeks often produce subtle changes that are easy to overlook
do not double up doses
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