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Bioavailability is a critical measure in pharmacology, indicating how much of a given dose of a drug is available to produce a therapeutic effect

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On the contrary, lower GSH levels were also recorded among males of Group B, which might be related to several factors, including more rapid utilization against increased oxidative stress caused by testosterone and sex-dependent regulation of GSH metabolism

[23] The duration of therapy (number of weeks or months of injections) is also determined on a case-by-case basis

We also show that the maintenance of redox balance via glutathione recycling is an essential process in Bd , as inhibition of GR activity is acutely toxic